Ocular Inserts - The Final Say in Ocular Drug Delivery?
Ocular drug delivery is where drugs are directly administered to the eye via injections/eye drops. It is one of the most challenging aspects of ocular pharmacology. Patients requiring injections have to go out of their way to attend uncomfortable procedures at outpatient clinics. The efficacy of eye drops is dependent on the patient’s skills, but even the perfect placement of eye drops will only result in 1-10% of the total administered dose being absorbed. These cons are responsible for low patient compliance, and consequently worse outcomes than predicted. After 20 years of trialling new ocular drug vehicles, ophthalmic pharmacies have devised ocular inserts as a novel solution. Their administration is speedier and more comfortable for the patient, they ensure better drug absorption at a regular rate, and they don’t have to be replaced as frequently. Ocular inserts are thin, drug-impregnated devices placed into the cul-de-sac or conjunctival sac of the eye. They can release steroids ...